Examining Genetics for Families of Patients with Gastrointestinal Cancer: Addressing Challenges in Rural Communities
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Course Description:
This course will review important topics regarding the identification and management of individuals with a hereditary gastrointestinal cancer condition. We will review standard practice guidelines from the National Comprehensive Cancer Care Network (NCCN) to determine when genetic testing for hereditary gastrointestinal cancers is appropriate and why gathering family history is important for this process. We will also discuss the fundamentals of mismatch repair immunohistochemistry (MMR IHC), as well as how to interpret complicated MMR IHC results using case examples. Additionally, resources to help with family history collection, genetic counseling, and genetic testing will be reviewed.
Target Audience:
The target audience for this project is providers in the state of Iowa involved in the care of patients at risk for hereditary gastrointestinal cancer conditions, such as primary care providers, advanced practice providers (nurse practitioners, physician assistants), surgeons, oncologists, gastroenterologists, nurses, nurse navigators, and pathologists.
Learning Objectives:
At the end of this educational program, participants should be able to:
- Identify patients and their family members at risk for a hereditary gastrointestinal cancer condition to offer genetic counseling and/or testing.
- Interpret mismatch repair immunohistochemistry (MMR IHC) results and use it appropriately as a screening versus diagnostic tool.
- Identify resources to help facilitate genetic testing, genetic counseling, and management for hereditary gastrointestinal cancer conditions.
Athena Puski, MS LGC
Licensed Genetic Counselor
Holden Comprehensive Cancer Center University of Iowa Hospitals and Clinics
Athena Puski is a licensed genetic counselor specializing in hereditary cancer. She obtained her master’s degree in genetic counseling from The Ohio State University. She has been providing genetic counseling and testing to patients and their family members for 7 years with the Holden Comprehensive Cancer Center at the University of Iowa Hospitals & Clinics. Athena works with all cancer types and adult-onset hereditary cancer conditions. She has also been working on ways to expand access to genetic counseling and testing across the state of Iowa.
Nicole Huser Blum, MS, LGC
Associate Licensed Genetic Counselor
Holden Comprehensive Cancer Center University of Iowa Hospitals & Clinics
Nicole Blum, MS, LGC is a native Iowan, born and raised in Sac City, Iowa. She obtained her Bachelor of Science degree in Genetics with a minor in Psychology from Iowa State University in 2019. Nicole then went on to the University of Michigan Genetic Counseling Program where she obtained her Master of Science in Genetic Counseling in 2021. While in graduate training, her thesis work surrounded gender inclusivity in genetic counseling practices, and she developed an online educational tool for genetic counselors on how to best serve patients who are transgender and/or gender diverse. For this work, she was awarded the Neel Genetic Counseling Fellowship as well as the Jane Engelberg Memorial Foundation Student Manuscript Award once it was published. Nicole began her clinical career in genetic counseling in her current role as a cancer genetic counselor at the University of Iowa, Holden Comprehensive Cancer Center following her graduation from the University of Michigan Genetic Counseling Program. In this role, Nicole sees patients with a personal and/or family history of cancer and is able to educate on the role genetics can play in cancer predisposition, genetic testing options, and the impact genetic information can have on patient’s lives. Nicole has been able to work particularly close with the gynecology oncology team at the Holden Comprehensive Cancer Center, as well as gastroenterology and melanoma multidisciplinary care providers. Through these partnerships, she has been able to educate these teams on National Comprehensive Cancer Network and American College of Medical Genetics Guidelines for genetic counseling and genetic testing. This has allowed for an increase in appropriate referrals to genetic counseling, and subsequent genetic testing information for many, to be used by these patients and their families for medical management and decision-making. Nicole also works closely with the other four genetic counselors at the Holden Comprehensive Cancer Center and the genetic counseling community as a whole at the University of Iowa. Nicole is an active member of the National Society of Genetic Counselors, American Board of Genetic Counseling, Iowa Oncology Society, Iowa Cancer Consortium, and the curriculum task force co-chair for the Inter-Society Coordinating Committee for Practitioner Education in Genomics- LGBTQ+ Workgroup through the NIH.