Optimizing Outcomes for HR+, HER2- Metastatic Breast Cancer
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Overview:
Most patients diagnosed with breast cancer have a subtype that is hormone receptor-positive (HR+) and human epidermal growth factor receptor 2-negative (HER2-). While this form of breast cancer is generally highly treatable in its earlier stages, some patients will unfortunately develop metastatic disease. However, the treatment landscape for HR+, HER2- metastatic breast cancer has seen significant advancements in recent years, with the introduction of new therapies that improve both quality of life and progression-free survival. These treatment options include endocrine therapies, CDK4/6 inhibitors, and antibody-drug conjugates (ADCs).
As the number of promising treatment options for patients with HR+, HER2- metastatic breast cancer expands, it remains a challenge for community oncology providers to stay abreast of the latest and most effective management strategies for their patients. To address this need, the Association of Cancer Care Centers (ACCC) is developing an educational series of 3 videos to equip community oncology providers with up-to-date education and information on evidence-based practices for managing treatment and care for this population.
Target Audience:
This continuing education activity is intended for physicians, physician assistants, nurses, pharmacists, APPs.
Fees:
This activity is free for all participants.
Activity Type:
Asynchronous online enduring consisting of 3 videos, pre- and post-activity assessments, and an activity evaluation.
Learning Objectives:
At the end of this educational activity, participants should be able to:
- Discuss evidence-based treatment for patients with HR+, HER2– metastatic breast cancer, including treatment selection strategies
- Outline evaluation and management for patients with potential treatment-related adverse events
- Describe practices that can improve quality of life and clinical outcomes in HR+, HER2– metastatic breast cancer
Accreditation/Designation of Credit:
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Physicians' Education Resource®, LLC and the Association of Cancer Care Centers (ACCC). Physicians' Education Resource®, LLC is accredited by the ACCME to provide continuing medical education for physicians.
Physicians' Education Resource®, LLC (PER) is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.
Physicians' Education Resource®, LLC designates this live activity for a maximum of 1.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians' Education Resource®, LLC has approved this application-based activity for 1.50 ACPE CE hours. The Universal Activity Number for this activity is 0661-9999-24-002-H01-P. Eligibility for credits requires engagement with all online activities, completion of pre- and post-activity assessments with a minimum passing score of 70%, and submission of activity evaluation, NABP e-pid# and month/date of birth within 45 days of activity completion. No partial credits are given. This UAN expires October 28. 2027.
Physicians’ Education Resource®, LLC is approved by the California Board of Registered Nursing (CBRN), Provider #16669, for 1.50 total Contact Hours. Eligibility for credits requires full attendance; no partial credits are given.
Faculty, Staff, and Planners:
Program Chair: Pavani Chalasani, MD, MPH · Professor of Medicine · George Washington University
Faculty: Allison Butts, PharmD, BCOP · Pharmacist Manager, Oncology · University of Kentucky, Pavani Chalasani, MD, MPH · Professor of Medicine · George Washington University, Claudia Franco, PA-C · Physician Assistant · Inova Schar Cancer Institute
Planners: Allison Butts, PharmD, BCOP · Pharmacist Manager, Oncology · University of Kentucky,Pavani Chalasani, MD, MPH · Professor of Medicine · George Washington University. Claudia Franco, PA-C · Physician Assistant · Inova Schar Cancer Institute, Molly Kisiel, NP · Director, Clinical Content · Association of Cancer Care Centers, Latha Shivakumar, PhD, CHCP · Director, Clinical Education Development · Association of Cancer Care Centers, Victoria Zwicker, MPH · Program Manager, Education Programs · Association of Cancer Care Centers
Disclosures and Conflict of Interest (COI) Mitigation:
The following individuals have no relevant financial relationships with ineligible companies to disclose: Allison Butts, PharmD, BCOP; Claudia Franco, PA-C; Molly Kisiel, NP; Latha Shivakumar, PhD, CHCP; Victoria Zwicker, MPH; the staffs of ACCC and Physicians’ Education Resource®, LLC.
Pavani Chalsani, MD, MPH - Grant/Research Support: Pfizer, Stemline Therapeutics, Vaxiion Therapeutics, Inc., Personalis, Immutep
PER® has identified and mitigated all COI prior to the start of this activity by using a multistep process.
How to Request Credit:
To complete the online evaluation(s) and receive a certificate of credit or participation, please visit the post-activity evaluation instructional document embedded in the activity.
Off-Label Disclosure and Disclaimer: This CE activity may or may not discuss investigational, unapproved, or off-label uses of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CE activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician, nurse, or pharmacist relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of Physicians’ Education Resource®, LLC or ACCC.
Funding:
This activity is supported by an educational grant from AstraZeneca.
Technology Requirements:
For the best registration and viewing experience, please use Chrome, Edge, or Safari web browsers. Internet Explorer Users may experience difficulties accessing the webinar.
Refund Policy:
As the program is free, refunds are not applicable.
Dr. Allison Butts, PharmD
Pharmacist Manager- Oncology Pharmacy
UK Healthcare, UK Healthcare Markey Cancer Center, Lexington, KY
Dr. Butts is the oncology pharmacy manager at UK HealthCare and specializes in clinical pharmacy for breast oncology. She received her Bachelor of Science degree in molecular and cellular biology from the University of Illinois at Urbana-Champaign, and her Doctor of Pharmacy degree from the University of Kentucky. She then completed a PGY1 pharmacy practice residency at The Johns Hopkins Hospital and a PGY2 oncology residency at the University of Kentucky Chandler Medical Center. Dr. Butts provides comprehensive pharmaceutical care to patients at the UK Markey Cancer Center, primarily practicing at the Comprehensive Breast Care Center. Additionally, she serves as the PGY2 hematology-oncology pharmacy residency program director and is an assistant adjunct professor at the University of Kentucky College of Pharmacy.
Dr. Pavani Chalasani MD, MPH
Hematologist-Oncologist, Division Director, Hematology-Oncology
George Washington Cancer Center (GWCC), Washington, D.C.
Dr. Chalasani is the director of the hematology-oncology division at the George Washington Cancer Center (GWCC) and co-program lead for the Clinical Translational Oncology Program. After receiving her medical degree from Gandhi Medical College in India, she completed internship, residency and a fellowship in hematology-oncology at the University of Arizona, Tucson. She joined the University of Arizona Cancer Center (UACC) as a faculty member and served as program director for the hematology-oncology fellowship program. Dr. Chalasani is the principal investigator for several clinical trials and was awarded the prestigious NCI Clinical Cancer Investigator Team Leadership Award in 2020. She has received research funding from NIH/NCI, American Cancer Society, Better Than Ever and DOD.
Claudia Y. Franco, PA-C
Physician Assistant
Inova Schar Cancer Institute, Fairfax, VA
Claudia Franco is a certified physician assistant serving at Inova Schar Cancer Institute in Fairfax, VA providing patient care in the outpatient setting. She strives to provide evidence-based compassionate care to patients with medical oncology and hematology needs. Claudia has a passion for community outreach and providing care to underserved patient populations. She serves as a sub-investigator for several clinical trials in breast cancer at Inova and is a member of the Advanced Practitioner Society for Hematology and Oncology.